FIT screening

Colorectal cancer (CRC) is one of the most frequently diagnosed cancers. The good news is that CRC incidence and mortality can be reduced significantly if detected early enough.

Faecal immunochemical tests (FIT) are non-invasive and can detect blood in stool invisible to the naked eye. Due to its simplicity, FIT is currently considered the best non-invasive test for CRC screening.

Invest a little time in your own health by taking the FIT to prevent or detect colon cancer early on.
For further information, please visit our ‘FIT for screening’ website www.fitscreening.eu/patients

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NRBC channel

In the NRBC channel, a surfactant in the Stromatolyser-NR reagent lyses the red blood cell membranes, leaving only the nuclei of nucleated red blood cells (NRBC) intact. It also perforates the cell membrane of white blood cells, in which the polymethine fluorescence marker of stromatolyser-NR  labels the nucleic acids in the nuclei as well as cytoplasmic organelles.

NRBC, on the other hand, have lost their cytoplasm after the reaction so that the fluorescence marker only labels nucleic acids in the nucleus. This results in two distinct populations based on differences in fluorescence intensity. NRBC are separated from white blood cells due to their lower fluorescence intensity.

The white blood cell and lymphocyte count results are automatically corrected if NRBC are detected in the NRBC channel, prior to reporting. 

This channel is only available on XE-2100 and XE-5000.

Analyser channels

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